The patient now becomes progressively more vasoconstricted and hypotensive. Volume replacement is tried, but fails to raise the cardiac index and results in a rise of the pulmonary wedge pressure to 32. PVC's rise to 6/min. Urine output falls to 10 cc/hr. A mild metabolic acidosis is present: pH 7.30, pCO2 38, HCO3 17. How would you proceed?